CareLit · DOI-Nachweis · Klinische Pädiatrie
Pivotal Role of the Serum- and Glucocorticoid-inducible kinase 1 in Rhabdomyosarcoma
DOI 10.1055/s-0035-1550260
Bibliografische Angaben
Nachweis in CareLit
Autor:innenE Schmid, J Yang, F Lang, G Seitz, J Fuchs
ZeitschriftKlinische Pädiatrie
Ausgabe07/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: The serum-and-glucocorticoid-inducible-kinase-1 (SGK1) is ubiquitously expressed. Expression of SGK1 is normally low in most cells, but is dramatically upregulated under pathophysiological conditions, like hypertension, diabetes and tumor growth. SGK1 increases the store operated Ca2+ entry (SOCE), which is accomplished by the pore forming ion channel unit Orai1 and its regulator STIM1. Methods: Transc…
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Zitierempfehlung
E Schmid, J Yang, F Lang, G Seitz, J Fuchs (2015) Pivotal Role of the Serum- and Glucocorticoid-inducible kinase 1 in Rhabdomyosarcoma. Klinische Pädiatrie (07). https://doi.org/10.1055/s-0035-1550260
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