CareLit · DOI-Nachweis · Senologie - Zeitschrift für Mammadiagnostik und -therapie
EpCAM-independent enrichment approach for isolation of circulating tumor cells (CTCs) in breast cancer – What can be found in the EpCAM-depleted fraction?
DOI 10.1055/s-0035-1550566
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Nachweis in CareLit
Autor:innenH Schneck, B Gierke, M Pawlak, M Templin, T Fehm, D Niederacher, H Neubauer
ZeitschriftSenologie - Zeitschrift für Mammadiagnostik und -therapie
Ausgabe05/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
CTCs are essential for establishing metastasis in breast cancer. While many assays currently exist for the enumeration of CTCs, limitations include the reliance on the expression of the cell surface marker epithelial cell adhesion molecule (EpCAM). These approaches may omit CTCs expressing either no/low levels of EpCAM, eventually representing the metastasis-initiating population. In order to successfully capture Ep…
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Zitierempfehlung
H Schneck, B Gierke, M Pawlak, M Templin, T Fehm, D Niederacher, H Neubauer (2015) EpCAM-independent enrichment approach for isolation of circulating tumor cells (CTCs) in breast cancer – What can be found in the EpCAM-depleted fraction?. Senologie - Zeitschrift für Mammadiagnostik und -therapie (05). https://doi.org/10.1055/s-0035-1550566
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