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Metabolomics profiling identifies long-chain phosphatidyl-cholines as a potential causative link between iron and insulin resistance in NAFLD

L Stechemesser, D Niederseer, A Wagner, T Felder, A Stadlmayr, S Eder, M Strasser, C Datz, E Aigner · Zeitschrift für Gastroenterologie · Ausgabe 05/2015

DOI 10.1055/s-0035-1551685

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Autor:innenL Stechemesser, D Niederseer, A Wagner, T Felder, A Stadlmayr, S Eder, M Strasser, C Datz, E Aigner
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe05/2015
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Background: Elevated serum ferritin has been linked NAFLD and adverse outcomes in subjects with the Metabolic Syndrome (MetS). As the mechanisms underlying the negative impact of excess iron have so far remained elusive, we aimed to identify potential pathways using a metabolomics analysis. Methods: In all subjects, a detailed clinical and biochemical characterization was obtained. Metabolomics profiling was perform…

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L Stechemesser, D Niederseer, A Wagner, T Felder, A Stadlmayr, S Eder, M Strasser, C Datz, E Aigner (2015) Metabolomics profiling identifies long-chain phosphatidyl-cholines as a potential causative link between iron and insulin resistance in NAFLD. Zeitschrift für Gastroenterologie (05). https://doi.org/10.1055/s-0035-1551685

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