CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Oxidative stress is a driver of chromosomal instability and tumorigenesis in IL-10KO mice
DOI 10.1055/s-0035-1551696
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Nachweis in CareLit
Autor:innenA Frick
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe05/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Patients with inflammatory bowel disease like Crohn's disease (CD) and ulcerative colitis (UC) have a higher risk of developing colitis-associated cancer (CAC); however, the underlying mechanism of disease progression from colitis to CAC is not well understood. IL-10 and IL-10R polymorphism are implicated by GWAS studies in susceptibility for UC. In inflammation-driven carcinogenesis, genetic instability and oncogen…
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Zitierempfehlung
A Frick (2015) Oxidative stress is a driver of chromosomal instability and tumorigenesis in IL-10KO mice. Zeitschrift für Gastroenterologie (05). https://doi.org/10.1055/s-0035-1551696
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