CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Lipocalin2 protects from severe inflammation in IL-10 knockout mice
DOI 10.1055/s-0035-1551700
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Nachweis in CareLit
Autor:innenRR Gerner, AR Moschen, J Wang, A Pfister, TE Adolph, H Tilg
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe05/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction & Aims: The antibacterial protein neutrophil gelatinase-associated lipocalin (NGAL or Lipocalin-2 (Lcn2)) plays a central role during infections by sequestrating iron and thus suppressing bacterial growth and promoting their clearance. However its function in mucosal gut immunity has not yet been identified. Lcn2 is highly upregulated in human inflammatory bowel diseases (IBD). Similarly, we observed a…
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Zitierempfehlung
RR Gerner, AR Moschen, J Wang, A Pfister, TE Adolph, H Tilg (2015) Lipocalin2 protects from severe inflammation in IL-10 knockout mice. Zeitschrift für Gastroenterologie (05). https://doi.org/10.1055/s-0035-1551700
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