CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Treatment of biliary tract cancer cells with polycomb repressive complex 1 inhibitor PTC-209 reduces putative cancer stem cell population and causes cell cycle arrest
DOI 10.1055/s-0035-1551755
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Autor:innenC Mayr, A Wagner, M Beyreis, R Illig, F Berr, M Pichler, P Di Fazio, D Neureiter, T Kiesslich
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe05/2015
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Question: The polycomb repressive complex 1 (PRC1) is an epigenetic regulator that plays a crucial role in various types of cancer including biliary tract cancer (BTC). BTC is a fatal disease associated with poor outcome. Hence, new therapeutic strategies are needed. Recently, the first small-molecule PRC1 inhibitor called PTC-209 has been developed. In this study, we examined the effect of PTC-209 on eight differen…
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Zitierempfehlung
C Mayr, A Wagner, M Beyreis, R Illig, F Berr, M Pichler, P Di Fazio, D Neureiter, T Kiesslich (2015) Treatment of biliary tract cancer cells with polycomb repressive complex 1 inhibitor PTC-209 reduces putative cancer stem cell population and causes cell cycle arrest. Zeitschrift für Gastroenterologie (05). https://doi.org/10.1055/s-0035-1551755
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