CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The soluble guanylyl cyclase stimulator riociguat reduces liver fibrosis and portal pressure in cirrhotic rats
DOI 10.1055/s-0035-1551789
Bibliografische Angaben
Nachweis in CareLit
Autor:innenP Schwabl, K Brusilovskaya, F Riedl, D Bauer, B Strobel, S Fida, P Supper, H Hayden, M Trauner, M Peck-Radosavljevic, T Reiberger
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe05/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: In liver cirrhosis nitric oxide (NO) signaling, including function of its receptor soluble guanylyl cyclase (sGC), is distorted. The sGC stimulator riociguat (RIO) is used as treatment for pulmonary hypertension and it has been shown that RIO acts antifibrotic. We thus aimed to investigate effects of RIO on experimental liver cirrhosis and portal hypertension. Methods: Cirrhosis was induced by carbontetr…
Zitieren
Zitierempfehlung
P Schwabl, K Brusilovskaya, F Riedl, D Bauer, B Strobel, S Fida, P Supper, H Hayden, M Trauner, M Peck-Radosavljevic, T Reiberger (2015) The soluble guanylyl cyclase stimulator riociguat reduces liver fibrosis and portal pressure in cirrhotic rats. Zeitschrift für Gastroenterologie (05). https://doi.org/10.1055/s-0035-1551789
Mit CareLit weiterarbeiten