CareLit · DOI-Nachweis · Pneumologie
Cigarette smoke exposure enhances obstructive bronchitis in ENaC overexpressing newborn-mice
DOI 10.1055/s-0035-1551906
Bibliografische Angaben
Nachweis in CareLit
Autor:innenJ Jia, TM Conlon, C Ballester Lopez, O Eickelberg, MA Mall, AÖ Yildirim
ZeitschriftPneumologie
Ausgabe05/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Chronic bronchitis (CB) is characterized by mucus accumulation, airway neutrophilia, and chronic airway obstruction. Excess mucus production, together with less efficient cough and loss of normal ciliary function, leads to recurrent airflow limitation, airway remodeling and respiratory obstruction. Overexpression of Na+ ion channels (βENaC) in the airway epithelial membrane of mice leads to airway surface liquid dep…
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Zitierempfehlung
J Jia, TM Conlon, C Ballester Lopez, O Eickelberg, MA Mall, AÖ Yildirim (2015) Cigarette smoke exposure enhances obstructive bronchitis in ENaC overexpressing newborn-mice. Pneumologie (05). https://doi.org/10.1055/s-0035-1551906
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