CareLit · DOI-Nachweis · Pneumologie
Glucocorticoids and IL-13 modulate the barrier function of NCI-H441 airway epithelia via claudin 8
DOI 10.1055/s-0035-1551908
Bibliografische Angaben
Nachweis in CareLit
Autor:innenVE Winkelmann, H Schmidt, F Kielgast, M Frick, P Dietl, OH Wittekindt
ZeitschriftPneumologie
Ausgabe05/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: In allergic asthma elevated levels of TH2 cytokines, especially IL-13 levels can be observed. Allergic asthma is typically treated with Glucocorticoids (GCs), whose anti-inflammatory properties are the predominant objective of this treatment. Recent studies showed an additional GC effect on the barrier function of the airway epithelium and identified claudin 8 (cldn8) as a major modulator of tight junc…
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Zitierempfehlung
VE Winkelmann, H Schmidt, F Kielgast, M Frick, P Dietl, OH Wittekindt (2015) Glucocorticoids and IL-13 modulate the barrier function of NCI-H441 airway epithelia via claudin 8. Pneumologie (05). https://doi.org/10.1055/s-0035-1551908
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