CareLit · DOI-Nachweis · Pneumologie
Contribution of meprin β in lung fibrosis
DOI 10.1055/s-0035-1551912
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Nachweis in CareLit
Autor:innenV Biasin, M Wygrecka, A Gungl, B Ghanim, W Klepetko, LM Marsh, A Olschewski, G Kwapiszewska
ZeitschriftPneumologie
Ausgabe05/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Lung fibrosis is a severe disease which is characterized by collagen deposition and stiffening of the lung. Over-expression of the transcription factor fra-2 in mice (fra-2 tg) leads to an increase of the inflammatory infiltrate, pro-fibrogenic factors and to development of lung fibrosis, which resembled the human idiopathic pulmonary fibrosis (IPF). The protease meprin β is the most upregulated gene i…
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Zitierempfehlung
V Biasin, M Wygrecka, A Gungl, B Ghanim, W Klepetko, LM Marsh, A Olschewski, G Kwapiszewska (2015) Contribution of meprin β in lung fibrosis. Pneumologie (05). https://doi.org/10.1055/s-0035-1551912
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