CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Liver sinusoidal endothelial cells (LSECs) isolated ex vivo by a novel MACS-based technology induce proliferation in naïve CD4+ T-cells and Th2 effector cells
DOI 10.1055/s-0035-1555376
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Nachweis in CareLit
Autor:innenA Schrage, PA Knolle, M Zeitz, A Hamann, K Klugewitz
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe05/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The liver has been demonstrated to contribute to the induction of systemic tolerance by trapping, deletion or modulation of T-cells. This property seems to be at least partially mediated by liver sinusoidal endothelial cells (LSECs) since in vivo priming of CD8+ T-cells on LSECs leads to development of anergic T-cell subsets. Studying the function of endothelial cells (ECs) ex vivo usually meets experimental obstacl…
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Zitierempfehlung
A Schrage, PA Knolle, M Zeitz, A Hamann, K Klugewitz (2015) Liver sinusoidal endothelial cells (LSECs) isolated ex vivo by a novel MACS-based technology induce proliferation in naïve CD4+ T-cells and Th2 effector cells. Zeitschrift für Gastroenterologie (05). https://doi.org/10.1055/s-0035-1555376
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