CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Absence of CXCL10 prolongs islet graft survival in an autoimmune mouse model for Type 1 Diabetes
DOI 10.1055/s-0035-1556570
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Autor:innenC Bender, S Christen, E Hintermann, U Christen
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe08/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Type 1 diabetes (T1D) results from the autoimmune destruction of insulin-producing beta-cells in the pancreas. The chemokine CXCL10 seems to play an important role in the recruitment of autoaggressive lymphocytes to the islets of Langerhans in Type 1 Diabetes (T1D). Since transplantation of isolated islets is a promising therapy of T1D, but has been hampered by the fact that islet grafts get rejected even in presenc…
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Zitierempfehlung
C Bender, S Christen, E Hintermann, U Christen (2015) Absence of CXCL10 prolongs islet graft survival in an autoimmune mouse model for Type 1 Diabetes. Diabetologie und Stoffwechsel (08). https://doi.org/10.1055/s-0035-1556570
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