CareLit · DOI-Nachweis · Pneumologie
Dysregulation of epithelial miR-148b contributes to goblet cell metaplasia, inflammation and alveolar damage in cystic fibrosis lung disease
DOI 10.1055/s-0035-1556595
Bibliografische Angaben
Nachweis in CareLit
Autor:innenR Agrawal, S Altamura, F Stanke, M Meister, T Muley, SH Randell, CM Greene, B Tümmler, MU Muckenthaler, MA Mall
ZeitschriftPneumologie
Ausgabe07/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Cystic fibrosis (CF) lung disease is primarily characterized by chronic mucus obstruction, inflammation and structural damage. While mutations in the CFTR gene are an initial trigger, molecular mechanisms underlying CF pathogenesis remains poorly understood. miRNAs are key regulators of diverse biological and pathological processes. Here, we identified association of miR-148b during the in vivo pathogenesis of CF us…
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Zitierempfehlung
R Agrawal, S Altamura, F Stanke, M Meister, T Muley, SH Randell, CM Greene, B Tümmler, MU Muckenthaler, MA Mall (2015) Dysregulation of epithelial miR-148b contributes to goblet cell metaplasia, inflammation and alveolar damage in cystic fibrosis lung disease. Pneumologie (07). https://doi.org/10.1055/s-0035-1556595
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