CareLit · DOI-Nachweis · Pneumologie
MiR-210 and miR-155 are Upregulated in CFBE Cells and Involved in Fe-S Protein Assembly via ISCU Downregulation as well as HO-1 Expression via BACH1.
DOI 10.1055/s-0035-1556596
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Nachweis in CareLit
Autor:innenS Chillappagari, V Garapati, P Mahavadi, O Stehling, R Lill, B Schmeck, M Henke
ZeitschriftPneumologie
Ausgabe07/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Cystic fibrosis (CF) is an inherited lung disorder associated with chronic endobronchial inflammation. Hemeoxygenase-1 (HMOX1), an enzyme involved in heme degradation, is upregulated in inflammation and negatively regulated via the transcription factor BACH1. Here we studied the role of microRNAs (miRs) in the heme metabolism of cystic fibrosis bronchial epithelial cells (CFBE41o-), applying qRT-PCR, luciferase prom…
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Zitierempfehlung
S Chillappagari, V Garapati, P Mahavadi, O Stehling, R Lill, B Schmeck, M Henke (2015) MiR-210 and miR-155 are Upregulated in CFBE Cells and Involved in Fe-S Protein Assembly via ISCU Downregulation as well as HO-1 Expression via BACH1. Pneumologie (07). https://doi.org/10.1055/s-0035-1556596
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