CareLit · DOI-Nachweis · Pneumologie
Hematopoetic Stem Cell Transplantation and Genotyping in Cystic Fibrosis Mouse Model
DOI 10.1055/s-0035-1556603
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Nachweis in CareLit
Autor:innenS Hedtfeld, S Pratap Singh Sandhu, F Stanke, B Tümmler, A Munder
ZeitschriftPneumologie
Ausgabe07/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Although CF has been a target of gene therapy for decades, no viable approach is proven successful so far. Here, we attempted transplantation of hematopoietic stem and precursor cells (HSPCs) containing wild-type Cftr into Cftr-deficient mice to study restoration of CFTR function especially in non-epithelial cells. To accomplish this, we transplanted bone marrow from the wild-type BL6 and Cftr deficien…
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Zitierempfehlung
S Hedtfeld, S Pratap Singh Sandhu, F Stanke, B Tümmler, A Munder (2015) Hematopoetic Stem Cell Transplantation and Genotyping in Cystic Fibrosis Mouse Model. Pneumologie (07). https://doi.org/10.1055/s-0035-1556603
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