CareLit · DOI-Nachweis · Pneumologie
Neutrophil elastase activity on the surface of sputum neutrophils is associated with severity of airflow obstruction in cystic fibrosis
DOI 10.1055/s-0035-1556606
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Nachweis in CareLit
Autor:innenAS Dittrich, N Heath, M Wiebel, FJ Herth, C Schultz, MA Mall
ZeitschriftPneumologie
Ausgabe07/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Neutrophilic airway inflammation is a hallmark of cystic fibrosis (CF) and previous studies identified free neutrophil elastase (NE) in bronchoalveolar lavage fluid and sputum as a key risk factor of early bronchiectasis and decline in lung function. However, the relevance of membrane-associated NE activity in the pathophysiology of CF lung disease is not well understood. In this study, we used a ratio…
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Zitierempfehlung
AS Dittrich, N Heath, M Wiebel, FJ Herth, C Schultz, MA Mall (2015) Neutrophil elastase activity on the surface of sputum neutrophils is associated with severity of airflow obstruction in cystic fibrosis. Pneumologie (07). https://doi.org/10.1055/s-0035-1556606
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