CareLit · DOI-Nachweis · Pneumologie
Acute cigarette smoke accelerate chronic bronchitis development in ENaC overexpressing newborn-mice
DOI 10.1055/s-0035-1556610
Bibliografische Angaben
Nachweis in CareLit
Autor:innenJ Jia, TM Conlon, C Ballester López, O Eickelberg, MA Mall, A Önder Yildirim
ZeitschriftPneumologie
Ausgabe07/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Chronic bronchitis (CB) is characterized by mucus accumulation, airway neutrophilia, and chronic airway obstruction. Excess mucus production, together with less efficient cough and loss of normal ciliary function, leads to recurrent respiratory obstruction. Overexpression of Na+ ion channels (bENaC) in the airway epithelial membrane of mice leads to airway surface liquid depletion and mucocilia clearance dysfunction…
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Zitierempfehlung
J Jia, TM Conlon, C Ballester López, O Eickelberg, MA Mall, A Önder Yildirim (2015) Acute cigarette smoke accelerate chronic bronchitis development in ENaC overexpressing newborn-mice. Pneumologie (07). https://doi.org/10.1055/s-0035-1556610
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