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Monitoring protease activity in human sputum samples by FRET-based probes via statistics-based fluorescence image analysis

F Stein, N Heath, S Dittrich, MA Mall, C Schultz · Pneumologie · Ausgabe 07/2015

DOI 10.1055/s-0035-1556614

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Autor:innenF Stein, N Heath, S Dittrich, MA Mall, C Schultz
ZeitschriftPneumologie
Ausgabe07/2015
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

The activitiy of proteases play a crucial role in inflammatory processes as they contribute to white blood cell infiltration and the gradual destruction of the extracellular lung matrix in chronic inflammation. The activity levels of certain proteases such as neutrophil elastase (NE), cathepsin S and the matrix metalloproteases 9 and 12 (MMP-9, MMP-12) might be useful indicators for the progression of diseases such…

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Zitierempfehlung

F Stein, N Heath, S Dittrich, MA Mall, C Schultz (2015) Monitoring protease activity in human sputum samples by FRET-based probes via statistics-based fluorescence image analysis. Pneumologie (07). https://doi.org/10.1055/s-0035-1556614

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