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Characterization of the pulmonary immune response to Aspergillus fumigatus allergen in juvenile mice with reduced mucus clearance due to airway surface dehydration

C van Bodegom, J Schatterny, S Hirtz, MA Mall, B Fritzsching · Pneumologie · Ausgabe 07/2015

DOI 10.1055/s-0035-1556619

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Autor:innenC van Bodegom, J Schatterny, S Hirtz, MA Mall, B Fritzsching
ZeitschriftPneumologie
Ausgabe07/2015
Jahrgang / SeitenNicht angegeben

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Introduction: We have previously demonstrated that juvenile mice with airway overexpression of epithelial Na+ channels (βENaC-Tg) exhibit airway surface dehydration and eosinophilic airway inflammation (Mall MA, AmJRespirCritCareMed2008). We hypothesized that airway surface dehydration may increase the susceptibility for allergic airway inflammation towards Aspergillus fumigatus allergen (Af) and set out to characte…

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C van Bodegom, J Schatterny, S Hirtz, MA Mall, B Fritzsching (2015) Characterization of the pulmonary immune response to Aspergillus fumigatus allergen in juvenile mice with reduced mucus clearance due to airway surface dehydration. Pneumologie (07). https://doi.org/10.1055/s-0035-1556619

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