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Pulmonary IL-13 expression is increased by airway surface dehydration in vivo

S Christochowitz, C van Bodegom, S Schmidt, E Maier, M Hagner, J Fellenberg, MA Mall, B Fritzsching · Pneumologie · Ausgabe 07/2015

DOI 10.1055/s-0035-1556621

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Autor:innenS Christochowitz, C van Bodegom, S Schmidt, E Maier, M Hagner, J Fellenberg, MA Mall, B Fritzsching
ZeitschriftPneumologie
Ausgabe07/2015
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Introduction: We have previously demonstrated that mice with airway specific overexpression of the epithelial Na+ channel (βENaC-Tg) exhibit airway surface dehydration and eosinophilic airway inflammation in juvenile mice (Mall MA, Am J Respir Crit Care Med 2008). We hypothesized that airway surface dehydration may increase the susceptibility for allergic airway inflammation and treatment with allergen could induce…

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S Christochowitz, C van Bodegom, S Schmidt, E Maier, M Hagner, J Fellenberg, MA Mall, B Fritzsching (2015) Pulmonary IL-13 expression is increased by airway surface dehydration in vivo. Pneumologie (07). https://doi.org/10.1055/s-0035-1556621

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