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Airway surface dehydration is a novel risk factor for allergic airway inflammation

B Fritzsching, L Dai, C van Bodegom, J Schatterny, S Hirtz, Z Zhou-Suckow, M Hagner, S Christochowitz, MA Mall · Pneumologie · Ausgabe 07/2015

DOI 10.1055/s-0035-1556622

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Autor:innenB Fritzsching, L Dai, C van Bodegom, J Schatterny, S Hirtz, Z Zhou-Suckow, M Hagner, S Christochowitz, MA Mall
ZeitschriftPneumologie
Ausgabe07/2015
Jahrgang / SeitenNicht angegeben

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Introduction: We have previously demonstrated that mice with airway specific overexpression of the amiloride-sensitive epithelial Na+ channel (βENaC-Tg) and mice lacking the epithelial Cl- channel SLC26A9 suffer from airway surface dehydration and airway mucus obstruction, which might be implicated in the pathogenesis of allergic airway disease (Anagnostopoulou et al., JCI 2012 and Mall et al., AmJRespirCritCare Med…

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Zitierempfehlung

B Fritzsching, L Dai, C van Bodegom, J Schatterny, S Hirtz, Z Zhou-Suckow, M Hagner, S Christochowitz, MA Mall (2015) Airway surface dehydration is a novel risk factor for allergic airway inflammation. Pneumologie (07). https://doi.org/10.1055/s-0035-1556622

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