CareLit · DOI-Nachweis · Pneumologie
TRPA1 agonists modulate the trachealis muscle tone via two independent mechanisms
DOI 10.1055/s-0035-1556623
Bibliografische Angaben
Nachweis in CareLit
Autor:innenG Haider, JH Lee, S Wiegand, E Spies, HG Hoymann, W Kummer, A Braun, C Nassenstein
ZeitschriftPneumologie
Ausgabe07/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
TRPA1 is a cation channel of the transient receptor potential channel family that is predominantly expressed in sensory C-fibers and activated by a wide variety of environmental irritants and endogenous inflammatory mediators relevant for asthma. Activation increases [Ca2+]i, induces inward currents and action potential discharge in lung-innervating C-fibers in vitro and elicits central reflexes in vivo. However, it…
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Zitierempfehlung
G Haider, JH Lee, S Wiegand, E Spies, HG Hoymann, W Kummer, A Braun, C Nassenstein (2015) TRPA1 agonists modulate the trachealis muscle tone via two independent mechanisms. Pneumologie (07). https://doi.org/10.1055/s-0035-1556623
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