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Impact of embryonic Fgf10 expression deficiency on embryonic mouse lung development and hyperoxia lung injury

CM Chao, D Al Alam, R Schermuly, H Ehrhardt, KP Zimmer, S Bellusci · Pneumologie · Ausgabe 07/2015

DOI 10.1055/s-0035-1556625

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Autor:innenCM Chao, D Al Alam, R Schermuly, H Ehrhardt, KP Zimmer, S Bellusci
ZeitschriftPneumologie
Ausgabe07/2015
Jahrgang / SeitenNicht angegeben

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Introduction: Bronchopulmonary dysplasia (BPD), a chronic lung disease of preterm infants, is characterized by impaired alveolar growth and pathologic vascularization. We investigate the impact of Fgf10 expression deficiency on embryonic lung development and hyperoxia lung injury (BPD mouse model). Methods: Embryonic lungs (Fgf10+/- and Fgf10+/+[WT]) were harvested at E12.5 and E18.5. Lung branches were quantified a…

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CM Chao, D Al Alam, R Schermuly, H Ehrhardt, KP Zimmer, S Bellusci (2015) Impact of embryonic Fgf10 expression deficiency on embryonic mouse lung development and hyperoxia lung injury. Pneumologie (07). https://doi.org/10.1055/s-0035-1556625

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