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β-NAD inhibits ATP-mediated interleukin-1β release

S Hiller, A Zakrzewicz, S Wilker, I Jurastow, A Hecker, W Kummer, W Padberg, V Grau · Pneumologie · Ausgabe 07/2015

DOI 10.1055/s-0035-1556629

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Autor:innenS Hiller, A Zakrzewicz, S Wilker, I Jurastow, A Hecker, W Kummer, W Padberg, V Grau
ZeitschriftPneumologie
Ausgabe07/2015
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Introduction: Interleukin-1β (IL-1β) is a potent pro-inflammatory cytokine, which plays a central role in host defense. High systemic IL-1β levels, however, can result in life-threatening systemic inflammation and acute lung injury. Release of IL-1β is typically controlled by two consecutive danger signals. Lipopolysaccharide (LPS) can be the first signal inducing the synthesis of pro-IL-1β. Extracellular ATP is a p…

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Zitierempfehlung

S Hiller, A Zakrzewicz, S Wilker, I Jurastow, A Hecker, W Kummer, W Padberg, V Grau (2015) β-NAD inhibits ATP-mediated interleukin-1β release. Pneumologie (07). https://doi.org/10.1055/s-0035-1556629

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