CareLit · DOI-Nachweis · Pneumologie
Preserved right ventricular function in mitochondrial uncoupling protein 2 deficient mice in pressure overload induced right ventricular insufficiency
DOI 10.1055/s-0035-1556635
Bibliografische Angaben
Nachweis in CareLit
Autor:innenA Esfandiary, N Sommer, O Pak, B Kojonazarov, A Sydykov, D Haag, M Hecker, W Seeger, HA Ghofrani, R Schermuly, N Weissmann, R Schulz, R Schreckenberg, KD Schlüter
ZeitschriftPneumologie
Ausgabe07/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Right ventricular (RV) insufficiency is caused by RV pressure overload, when mechanisms compensating the increased afterload cannot maintain RV function. Similar to the left ventricle, compensatory and decompensatory mechanisms may be regulated by cellular calcium dynamics and reactive oxygen species (ROS). The mitochondrial uncoupling protein 2 (UCP2) can regulate mitochondrial calcium and ROS, and thus may interfe…
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Zitierempfehlung
A Esfandiary, N Sommer, O Pak, B Kojonazarov, A Sydykov, D Haag, M Hecker, W Seeger, HA Ghofrani, R Schermuly, N Weissmann, R Schulz, R Schreckenberg, KD Schlüter (2015) Preserved right ventricular function in mitochondrial uncoupling protein 2 deficient mice in pressure overload induced right ventricular insufficiency. Pneumologie (07). https://doi.org/10.1055/s-0035-1556635
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