CareLit · DOI-Nachweis · Pneumologie
Differentiation of human embryonic and induced pluripotent stem cells into CFTR expressing cholangiocytes for drug screening and disease modeling
DOI 10.1055/s-0035-1556639
Bibliografische Angaben
Nachweis in CareLit
Autor:innenR Haller, L Engels, S Merkert, M Schubert, O Ruth, M Ulrich
ZeitschriftPneumologie
Ausgabe07/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Cystic fibrosis (CF) is the most common lethal monogenic recessive disease in the caucasian population. While the majority of patients die of respiratory failure, hepatobiliary disease is the third leading cause of death in CF. Over 1900 mutations are known so far in cystic fibrosis transmembrane conductance regulator (CFTR) gene, but the most common is the ΔF508 mutation, resulting in enhanced degrada…
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Zitierempfehlung
R Haller, L Engels, S Merkert, M Schubert, O Ruth, M Ulrich (2015) Differentiation of human embryonic and induced pluripotent stem cells into CFTR expressing cholangiocytes for drug screening and disease modeling. Pneumologie (07). https://doi.org/10.1055/s-0035-1556639
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