CareLit · DOI-Nachweis · Pneumologie
Lung aging in C57/Bl6 and BALB/c mice is characterized by defects in surfactant metabolism, increased ER stress-signalling and inflammasome formation
DOI 10.1055/s-0035-1556649
Bibliografische Angaben
Nachweis in CareLit
Autor:innenM Korfei, D Klaus, D Stelmaszek, I Henneke, W Seeger, A Guenther
ZeitschriftPneumologie
Ausgabe07/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Accelerated lung aging is observed in both idiopathic pulmonary fibrosis (IPF) and chronic obstructive pulmonary disease (COPD). We performed phenotypical analyses of lungs from aged C57/Bl6 mice (24 months, n = 15) and BALB/c mice (18 month, n = 12) in comparison to young animals of both strains (6 weeks, n = 12) in order to elucidate the mechanisms of lung aging. Methods: Murine lung tissue was analy…
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Zitierempfehlung
M Korfei, D Klaus, D Stelmaszek, I Henneke, W Seeger, A Guenther (2015) Lung aging in C57/Bl6 and BALB/c mice is characterized by defects in surfactant metabolism, increased ER stress-signalling and inflammasome formation. Pneumologie (07). https://doi.org/10.1055/s-0035-1556649
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