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The role of ER stress mediators XBP1, ATF6 and ATF4 in AEC II apoptosis

I Shalashova, M Hühn, C Ruppert, O Klymenko, I Henneke, A Günther · Pneumologie · Ausgabe 07/2015

DOI 10.1055/s-0035-1556651

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Autor:innenI Shalashova, M Hühn, C Ruppert, O Klymenko, I Henneke, A Günther
ZeitschriftPneumologie
Ausgabe07/2015
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Idiopathic pulmonary fibrosis (IPF) is a lethal lung disease that more frequently affects older adults, with an estimated prevalence of 1.6 to 1.7 per 10,000 persons, and a median survival of 2 – 5 years. Although the pathogenesis of IPF is not clearly understood, it is considered that cronic injury of the alveolar epithelial cells (AEC) is the key event in IPF development. As AECII are responsible for alveolar epit…

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Zitierempfehlung

I Shalashova, M Hühn, C Ruppert, O Klymenko, I Henneke, A Günther (2015) The role of ER stress mediators XBP1, ATF6 and ATF4 in AEC II apoptosis. Pneumologie (07). https://doi.org/10.1055/s-0035-1556651

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