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Iron levels define two populations of Tumor Associated Macrophages

M Costa da Silva, M Correia, F Vinchi, A Cerwenka, MU Muckenthaler · Pneumologie · Ausgabe 07/2015

DOI 10.1055/s-0035-1556667

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Autor:innenM Costa da Silva, M Correia, F Vinchi, A Cerwenka, MU Muckenthaler
ZeitschriftPneumologie
Ausgabe07/2015
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Tumor-associated macrophages (TAMs) play an important role in the tumor microenvironment. TAMs acquire a M2-like macrophage phenotype and contribute to tissue remodeling, tumor growth and angiogenesis, hallmarks for cancer invasion. Likely, they also recycle iron from erythrocytes released as a consequence of angiogenesis in the tumor or retain iron upon tumor-related inflammation. The functional consequences of iro…

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Zitierempfehlung

M Costa da Silva, M Correia, F Vinchi, A Cerwenka, MU Muckenthaler (2015) Iron levels define two populations of Tumor Associated Macrophages. Pneumologie (07). https://doi.org/10.1055/s-0035-1556667

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