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Comprehensive modelling of multiple cell types reveals differences in Epo receptor signaling in primary erythroid and lung cancer cells

R Merkle, B Steiert, F Salopiata, S Depner, A Raue, C Kreutz, M Schelker, M Wäsch, ME Böhm, WD Lehmann, J Timmer, M Schilling, U Klingmüller · Pneumologie · Ausgabe 07/2015

DOI 10.1055/s-0035-1556668

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Autor:innenR Merkle, B Steiert, F Salopiata, S Depner, A Raue, C Kreutz, M Schelker, M Wäsch, ME Böhm, WD Lehmann, J Timmer, M Schilling, U Klingmüller
ZeitschriftPneumologie
Ausgabe07/2015
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Lung cancer with its most prevalent form non-small-cell lung carcinoma (NSCLC) is one of the leading causes of cancer-related deaths worldwide and is commonly treated with chemotherapeutic drugs, e.g. cisplatin. Lung cancer patients frequently suffer from chemotherapy-induced anemia, which can be treated with erythropoietin (Epo). However, recent studies have indicated that Epo may not only induce erythropoiesis in…

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R Merkle, B Steiert, F Salopiata, S Depner, A Raue, C Kreutz, M Schelker, M Wäsch, ME Böhm, WD Lehmann, J Timmer, M Schilling, U Klingmüller (2015) Comprehensive modelling of multiple cell types reveals differences in Epo receptor signaling in primary erythroid and lung cancer cells. Pneumologie (07). https://doi.org/10.1055/s-0035-1556668

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