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Chronic cocaine use is associated with glutamatergic and other neurometabolic alterations: a proton magnetic resonance spectroscopy study

LM Hulka, M Scheidegger, M Vonmoos, KH Preller, MR Baumgartner, M Herdener, E Seifritz, A Henning, BB Quednow · Suchttherapie · Ausgabe 08/2015

DOI 10.1055/s-0035-1557701

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Autor:innenLM Hulka, M Scheidegger, M Vonmoos, KH Preller, MR Baumgartner, M Herdener, E Seifritz, A Henning, BB Quednow
ZeitschriftSuchttherapie
Ausgabe08/2015
Jahrgang / SeitenNicht angegeben

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Introduction: Cocaine addiction is a chronically relapsing disorder that is associated with harmful consequences. Effective pharmacotherapies are sparse and the frequently occurring relapses remain a major challenge in the treatment of cocaine use disorder. Preclinical studies suggest that altered glutamatergic signaling from the prefrontal cortex to the nucleus accumbens core is crucial for the maintenance of cocai…

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LM Hulka, M Scheidegger, M Vonmoos, KH Preller, MR Baumgartner, M Herdener, E Seifritz, A Henning, BB Quednow (2015) Chronic cocaine use is associated with glutamatergic and other neurometabolic alterations: a proton magnetic resonance spectroscopy study. Suchttherapie (08). https://doi.org/10.1055/s-0035-1557701

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