CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Cathepsin D expression in pancreatic ductal adenocarcinoma (PDAC) cells increases proliferation and reduces survival of pancreatic cancer patients
DOI 10.1055/s-0035-1559095
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Nachweis in CareLit
Autor:innenU Mahajan, E Langhoff, E Costello, W Greenhalf, C Halloran, T Schwaiger, G Beyer, F Weiss, J Neoptolemos, T Kohlmann, M Maron, M Büchler, M Lerch, J Mayerle
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Remodelling of the pancreatic cancer tumour microenvironment and extracellular matrix (ECM) has been implicated in the prognosis of PDAC. We investigated whether the aspartic protease cathepsin-D contributes to proliferation, migration and fibrogenesis of pancreatic cancer and whether its expression affects the survival of pancreatic cancer patients. Material & Methods: Murine PSC and pancreatic cancer P…
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Zitierempfehlung
U Mahajan, E Langhoff, E Costello, W Greenhalf, C Halloran, T Schwaiger, G Beyer, F Weiss, J Neoptolemos, T Kohlmann, M Maron, M Büchler, M Lerch, J Mayerle (2015) Cathepsin D expression in pancreatic ductal adenocarcinoma (PDAC) cells increases proliferation and reduces survival of pancreatic cancer patients. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0035-1559095
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