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Effects of novel prosteatogenic TM6SF2 and NCAN/SUGP1 polymorphisms on hepatic steatosis and non-invasive markers of liver injury in patients with chronic liver diseases

A Arslanow, C Stokes, S Weber, F Grünhage, F Lammert, M Krawczyk · Zeitschrift für Gastroenterologie · Ausgabe 08/2015

DOI 10.1055/s-0035-1559109

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Autor:innenA Arslanow, C Stokes, S Weber, F Grünhage, F Lammert, M Krawczyk
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2015
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Previously we demonstrated that the frequent genetic variant PNPLA3 p.I148 M is associated with increased controlled attenuation parameter (CAP) and liver stiffness (LS) values in patients with chronic liver diseases (CLD). Recently single nucleotide variants in the TM6SF2 gene (rs58542926) and the NCAN/SUGP1 locus (rs10401969) have been reported as additional genetic determinants of fatty liver (Liu et al. Nat Comm…

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A Arslanow, C Stokes, S Weber, F Grünhage, F Lammert, M Krawczyk (2015) Effects of novel prosteatogenic TM6SF2 and NCAN/SUGP1 polymorphisms on hepatic steatosis and non-invasive markers of liver injury in patients with chronic liver diseases. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0035-1559109

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