CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Predictive value of genetically engineered endogenous mouse models in preclinical therapeutic studies
DOI 10.1055/s-0035-1559255
Bibliografische Angaben
Nachweis in CareLit
Autor:innenA Gupta, E Kalideris, M Trajkovic-Arsic, I Heid, R Braren, J Siveke
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies with an alarming resistance to both chemotherapeutics and targeted therapy approaches. Genetically engineered mouse models (GEMM) of PDAC reflect molecularly and pathophysiologically the carcinogenesis and cancer progression observed in humans, thus being excellent tools for preclinical evaluation of new therapies. To successfully pr…
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Zitierempfehlung
A Gupta, E Kalideris, M Trajkovic-Arsic, I Heid, R Braren, J Siveke (2015) Predictive value of genetically engineered endogenous mouse models in preclinical therapeutic studies. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0035-1559255
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