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Combination of the oral histone deacetylase inhibitor resminostat with oncolytic measles vaccine virus as a new option for epi-virotherapeutic treatment of hepatocellular carcinoma (HCC)

B Ruf, S Berchtold, S Venturelli, I Smirnow, T Prenzel, S Henning, U Lauer · Zeitschrift für Gastroenterologie · Ausgabe 08/2015

DOI 10.1055/s-0035-1559268

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Autor:innenB Ruf, S Berchtold, S Venturelli, I Smirnow, T Prenzel, S Henning, U Lauer
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2015
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Einleitung: Oncolytic viruses represent a novel therapeutic approach (so called virotherapy) in the treatment of malignant neoplasias, employing their ability to selectively infect, replicate in and (onco-) lyse tumor cells without affecting normal tissues. Nevertheless, in monotherapy virotherapeutics were found to face various limitations in recent clinical trials. To address those limitations, epigenetic compound…

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Zitierempfehlung

B Ruf, S Berchtold, S Venturelli, I Smirnow, T Prenzel, S Henning, U Lauer (2015) Combination of the oral histone deacetylase inhibitor resminostat with oncolytic measles vaccine virus as a new option for epi-virotherapeutic treatment of hepatocellular carcinoma (HCC). Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0035-1559268

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