CareLit · DOI-Nachweis · Klinische Pädiatrie
Hypothesis-driven “HDAC-autophagy” gene cluster to identify HDAC inhibitor treatment responsive tumor entities
DOI 10.1055/s-0035-1564668
Bibliografische Angaben
Nachweis in CareLit
Autor:innenE Koeneke, F Kolbinger, O Witt, I Oehme
ZeitschriftKlinische Pädiatrie
Ausgabe11/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Histone deacetylases (HDAC) have been identified as promising targets in the treatment of multiple types of cancer, including neuroblastoma and medulloblastoma. HDACs play important roles not only in histone modification resulting in chromatin remodeling and gene expression changes, but they also play direct roles in cellular processes including autophagy, apoptosis, cell mobility, and metabolism. Two histone deacet…
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Zitierempfehlung
E Koeneke, F Kolbinger, O Witt, I Oehme (2015) Hypothesis-driven “HDAC-autophagy” gene cluster to identify HDAC inhibitor treatment responsive tumor entities. Klinische Pädiatrie (11). https://doi.org/10.1055/s-0035-1564668
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