CareLit · DOI-Nachweis · Klinische Pädiatrie
Targeting MYC/HDAC2 interaction in Group 3 medulloblastoma – rationales for an innovative therapeutic approach
DOI 10.1055/s-0035-1564669
Bibliografische Angaben
Nachweis in CareLit
Autor:innenJ Ecker, I Oehme, A Korshunov, M Kool, AE Kulozik, SM Pfister, O Witt, T Milde
ZeitschriftKlinische Pädiatrie
Ausgabe11/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Medulloblastoma (MB) is one of the most frequent malignant brain tumors in children. Four subgroups with different molecular characteristics as well as differing clinical courses have been identified. In patients with Group 3 MBs overall survival remains particularly poor despite multimodal treatment. Group 3 and Group 4 tumors are characterized by modifications of their chromatin organizing machinery.…
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Zitierempfehlung
J Ecker, I Oehme, A Korshunov, M Kool, AE Kulozik, SM Pfister, O Witt, T Milde (2015) Targeting MYC/HDAC2 interaction in Group 3 medulloblastoma – rationales for an innovative therapeutic approach. Klinische Pädiatrie (11). https://doi.org/10.1055/s-0035-1564669
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