CareLit · DOI-Nachweis · Klinische Pädiatrie
Preclinical evaluation and translational consequences of EZH2-inhibition in malignant brain tumors
DOI 10.1055/s-0035-1564674
Bibliografische Angaben
Nachweis in CareLit
Autor:innenA Leibner, F Selt, J Ecker, I Oehme, M Kool, AE Kulozik, SM Pfister, O Witt, T Milde
ZeitschriftKlinische Pädiatrie
Ausgabe11/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Medulloblastoma (MB) and glioblastoma (GBM) belong to the most common malignant brain tumors in children, comprising distinct molecular and clinical entities, with in parts widely differing clinical outcomes. Recent sequencing efforts revealed that many mutations found in brain tumors impact chromatin-modifying functions. One of the processes targeted is histone methylation, in particular methylation o…
Zitieren
Zitierempfehlung
A Leibner, F Selt, J Ecker, I Oehme, M Kool, AE Kulozik, SM Pfister, O Witt, T Milde (2015) Preclinical evaluation and translational consequences of EZH2-inhibition in malignant brain tumors. Klinische Pädiatrie (11). https://doi.org/10.1055/s-0035-1564674
Mit CareLit weiterarbeiten