CareLit · DOI-Nachweis · Klinische Pädiatrie
Cell culture models of pediatric high-grade glioma are susceptible to parvovirus-1 induced cytotoxicity
DOI 10.1055/s-0035-1564676
Bibliografische Angaben
Nachweis in CareLit
Autor:innenR Josupeit, S Bender, B Leuchs, C Herold-Mende, JR Schlehofer, O Witt, J Rommelaere, J Jeannine Lacroix
ZeitschriftKlinische Pädiatrie
Ausgabe11/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Oncolytic viruses have entered the field of pediatric clinical research with the first early phase clinical trial recently published. Based on promising pre-clinical studies, the oncolytic parvovirus H-1 (H-1PV) has been applied to adult glioblastoma patients in a phase I/IIa clinical trial, indicating clinical safety of intracranial and intravenous virus application. Here, we characterized the cytotoxic effects ind…
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Zitierempfehlung
R Josupeit, S Bender, B Leuchs, C Herold-Mende, JR Schlehofer, O Witt, J Rommelaere, J Jeannine Lacroix (2015) Cell culture models of pediatric high-grade glioma are susceptible to parvovirus-1 induced cytotoxicity. Klinische Pädiatrie (11). https://doi.org/10.1055/s-0035-1564676
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