CareLit · DOI-Nachweis · Klinische Pädiatrie
Optimization of Glioblastoma multiforme in vitro culture conditions for preservation of EGFR gene amplification
DOI 10.1055/s-0035-1564677
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Nachweis in CareLit
Autor:innenD William, P Mokri, B Schneider, CF Classen
ZeitschriftKlinische Pädiatrie
Ausgabe11/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Glioblastoma multiforme (GBM) is the most common and lethal brain tumor. Numerous efforts are made to investigate cellular mechanisms in GBM tumor cells to develop more effective therapies. Hence, optimal in vitro models of GBM are essential, generated from individual patients and analysed at early passages to avoid culture artefacts. Different studies demonstrated that amplification of the egfr gene occurs in many…
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Zitierempfehlung
D William, P Mokri, B Schneider, CF Classen (2015) Optimization of Glioblastoma multiforme in vitro culture conditions for preservation of EGFR gene amplification. Klinische Pädiatrie (11). https://doi.org/10.1055/s-0035-1564677
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