CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
A new mouse model of sclerosing cholangitis combining toxic and immune mediated bile duct injury
DOI 10.1055/s-0035-1567937
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Autor:innenF Glaser, B Engel, C John, T Krech, A Carambia, J Herkel, AW Lohse, J Heeren, C Schramm, D Schwinge
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe12/2015
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Introduction: Primary Sclerosing Cholangitis (PSC) is a chronic cholestatic liver disease leading to fibrosis and obliteration of bile ducts, and eventually to cirrhosis and end stage liver disease. Currently there is no medical treatment with a proven benefit on disease progression. The etiology of PSC is largely unknown, but immune dysregulation and toxic biliary damage are considered to be part of PSC pathogenesi…
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Zitierempfehlung
F Glaser, B Engel, C John, T Krech, A Carambia, J Herkel, AW Lohse, J Heeren, C Schramm, D Schwinge (2015) A new mouse model of sclerosing cholangitis combining toxic and immune mediated bile duct injury. Zeitschrift für Gastroenterologie (12). https://doi.org/10.1055/s-0035-1567937
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