CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Hypoxia and inflammation reduce the expression of the mineralocorticoid receptor (MR) in the hepatocytes – a mechanism that explains the lower expression of MR in cirrhosis
DOI 10.1055/s-0035-1567954
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Nachweis in CareLit
Autor:innenA Wolf, B Schreier, S Hammer, S Pohl, M Gekle, A Zipprich
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe12/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Hypoxia and inflammation are the main mechanisms in the development of cirrhosis. Cirrhosis leads to increased concentration of aldosterone. Aldosterone activates the MR. The aim was to investigate the role of MR during the development of cirrhosis. Methods: Fibrosis and cirrhosis was induced by CCl4 administration for 5, 8 or 12 weeks (w). Total liver tissue, hepatocytes (Hep), hepatic stellate cells…
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Zitierempfehlung
A Wolf, B Schreier, S Hammer, S Pohl, M Gekle, A Zipprich (2015) Hypoxia and inflammation reduce the expression of the mineralocorticoid receptor (MR) in the hepatocytes – a mechanism that explains the lower expression of MR in cirrhosis. Zeitschrift für Gastroenterologie (12). https://doi.org/10.1055/s-0035-1567954
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