CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Increased expression of histone deacetylase 7 during hepatic stellate cell activation promotes pro-fibrogenic gene expression
DOI 10.1055/s-0035-1567956
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Autor:innenK Freese, C Dorn, WE Thasler, M Müller, C Hellerbrand
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe12/2015
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Recent evidence has highlighted a pathological imbalance in hepatic fibrosis between the acetylation and deacetylation of histone proteins regulated by histone deacetylases (HDACs). However, the role of individual HDACs in liver fibrosis is almost completely unknown. Recently, we identified that HDAC7 can bind to the promotor of the hepatocyte growth factor (HGF) gene, and herewith, suppresses the expression of this…
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Zitierempfehlung
K Freese, C Dorn, WE Thasler, M Müller, C Hellerbrand (2015) Increased expression of histone deacetylase 7 during hepatic stellate cell activation promotes pro-fibrogenic gene expression. Zeitschrift für Gastroenterologie (12). https://doi.org/10.1055/s-0035-1567956
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