CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Beneficial effects of IL-1 cytokine inactivation and the role of the serine/threonine kinase MK-2 in hepatic steatosis in a murine obesity model
DOI 10.1055/s-0035-1567978
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Nachweis in CareLit
Autor:innenJ Wohlfahrt, A Fettelschoss, T Kündig, H Hermanns, B Müllhaupt, J Schmitt, A Geier
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe12/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and Aims: Although non-alcoholic fatty liver disease (NAFLD) is among the most common causes of chronic liver disease worldwide, its pathogenesis is yet poorly understood. Recent studies show that the pro-inflammatory cytokines IL-1αand IL-1β play a crucial role in disease development. Their recognition by cells does not only result in transcriptional regulation of many IL-1 target genes, but also negativ…
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Zitierempfehlung
J Wohlfahrt, A Fettelschoss, T Kündig, H Hermanns, B Müllhaupt, J Schmitt, A Geier (2015) Beneficial effects of IL-1 cytokine inactivation and the role of the serine/threonine kinase MK-2 in hepatic steatosis in a murine obesity model. Zeitschrift für Gastroenterologie (12). https://doi.org/10.1055/s-0035-1567978
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