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Functional role of CCL5/RANTES for HCC progression during chronic liver disease: from humans to mice

A Mohs, N Kuttkat, J Reißing, HW Zimmermann, A Proudfoot, SA Youssef, A de Bruin, FJ Cubero, C Trautwein · Zeitschrift für Gastroenterologie · Ausgabe 12/2015

DOI 10.1055/s-0035-1567981

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Autor:innenA Mohs, N Kuttkat, J Reißing, HW Zimmermann, A Proudfoot, SA Youssef, A de Bruin, FJ Cubero, C Trautwein
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe12/2015
Jahrgang / SeitenNicht angegeben

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Background & Aims: Hepatocellular carcinoma (HCC) which is the consequence of malignant transformation of hepatocytes, is often based on chronic inflammation, resulting in liver fibrogenesis. During this process chemokines play a crucial role by attracting immune cells. In the current study, the function of CCL5/RANTES during chronic liver disease (CLD) was analysed in patients and two independent murine models of i…

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A Mohs, N Kuttkat, J Reißing, HW Zimmermann, A Proudfoot, SA Youssef, A de Bruin, FJ Cubero, C Trautwein (2015) Functional role of CCL5/RANTES for HCC progression during chronic liver disease: from humans to mice. Zeitschrift für Gastroenterologie (12). https://doi.org/10.1055/s-0035-1567981

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