CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Regenerative potential of human pluripotent stem cell-derived MSCs in a Gunn rat liver injury model
DOI 10.1055/s-0035-1568010
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Autor:innenLS Spitzhorn, M Megges, C Kordes, I Sawitza, S Götze, MA Kawala, W Wruck, R Oreffo, D Häussinger, J Adjaye
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe12/2015
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
The Crigler-Najjar syndrome type 1 is characterized by massively increased levels of unconjugated bilirubin in the plasma because of the lacking of hepatic uridine 5'-diphospho-glucuronosyltransferase activity (due to a mutated UGT1A1 gene) which is crucial for bilirubin conjugation and excretion. The Gunn rat is an in vivo model for this disease. Current treatments have several limitations therefore alternative the…
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Zitierempfehlung
LS Spitzhorn, M Megges, C Kordes, I Sawitza, S Götze, MA Kawala, W Wruck, R Oreffo, D Häussinger, J Adjaye (2015) Regenerative potential of human pluripotent stem cell-derived MSCs in a Gunn rat liver injury model. Zeitschrift für Gastroenterologie (12). https://doi.org/10.1055/s-0035-1568010
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