CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
iRhom2 regulates specific activation and trafficking of TACE and enhances the survival of TNF α mediated septic shock after LPS treatment
DOI 10.1055/s-0035-1568013
Bibliografische Angaben
Nachweis in CareLit
Autor:innenSM Maney, PA Lang
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe12/2015
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Innate immune responses are vital for pathogen defense but can result in septic shock when excessive. TNFα is a powerful inflammatory cytokines, which controls infection and also acts as a key mediator of septic shock. TNFα which is synthesized as a membrane- bound precursor, is liberated from the cell surface by the TNFα converting enzyme (TACE, also known as ADAM17). We report that the inactive rhomboid family mem…
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Zitierempfehlung
SM Maney, PA Lang (2015) iRhom2 regulates specific activation and trafficking of TACE and enhances the survival of TNF α mediated septic shock after LPS treatment. Zeitschrift für Gastroenterologie (12). https://doi.org/10.1055/s-0035-1568013
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