CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Deficiency of calcium-independent phospholipase A2 beta with aging causes biliary epithelial ductular reaction associated with increased bile acids in enterohepatic circulation
DOI 10.1055/s-0035-1568030
Bibliografische Angaben
Nachweis in CareLit
Autor:innenL Jiao, H Gan-Schreier, W Wei, S Tuma-Kellner, W Stremmel, W Chamulitrat
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe12/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background/Aims: Calcium-independent phospholipase A2 beta (iPLA2beta) generates lysophosphatidylcholine which is recognized as a macrophage 'fine me' signal for removal of apoptotic cells. We have shown that iPLA2beta deficiency causes an accumulation of apoptotic hepatocytes associated with a decrease of serum and hepatic lipids including cholesterol. We here determined whether iPLA2beta deficiency in aged mice ca…
Zitieren
Zitierempfehlung
L Jiao, H Gan-Schreier, W Wei, S Tuma-Kellner, W Stremmel, W Chamulitrat (2015) Deficiency of calcium-independent phospholipase A2 beta with aging causes biliary epithelial ductular reaction associated with increased bile acids in enterohepatic circulation. Zeitschrift für Gastroenterologie (12). https://doi.org/10.1055/s-0035-1568030
Mit CareLit weiterarbeiten