CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Identification of cytochrome CYP2E1 as critical mediator of synergistic effects of alcohol and cellular lipid accumulation in hepatocytes in vitro
DOI 10.1055/s-0035-1568037
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Autor:innenA Mahli, WE Thasler, E Patsenker, S Müller, F Stickel, M Müller, HK Seitz, AI Cederbaum, C Hellerbrand
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe12/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Clinical studies propose a causative link between the consumption of alcohol and the development and progression of liver disease in obese individuals. However, it is incompletely understood how alcohol and obesity interact and whether the combined effects are additive or synergistic. The aim of this study was to establish an in vitro model for joint effects of alcohol and steatosis in hepatocytes in vitro. Methods…
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Zitierempfehlung
A Mahli, WE Thasler, E Patsenker, S Müller, F Stickel, M Müller, HK Seitz, AI Cederbaum, C Hellerbrand (2015) Identification of cytochrome CYP2E1 as critical mediator of synergistic effects of alcohol and cellular lipid accumulation in hepatocytes in vitro. Zeitschrift für Gastroenterologie (12). https://doi.org/10.1055/s-0035-1568037
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