CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Lysophosphatidylcholine (LPC) as central player for control of hepatocellular fatty acid influx
DOI 10.1055/s-0035-1568042
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Autor:innenW Stremmel, S Staffer, A Wannhoff, A Pathil-Warth, W Chamulitrat
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe12/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: In NASH the intracellular ratio of phosphatidylcholine (PC): lysophosphatidylcholine (LPC) is decreased due to activation of phospholipase A2. Responsible is the calcium independent membrane phospholipase A2 (iPLA2β) which is part of the heterotetrameric fatty acid uptake complex consisting also of FABPPM, CD36 and caveolin1. The bile acid-phospholipid conjugate UDCA-LPE inhibits fatty acid influx by int…
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Zitierempfehlung
W Stremmel, S Staffer, A Wannhoff, A Pathil-Warth, W Chamulitrat (2015) Lysophosphatidylcholine (LPC) as central player for control of hepatocellular fatty acid influx. Zeitschrift für Gastroenterologie (12). https://doi.org/10.1055/s-0035-1568042
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